TY - JOUR

T1 - Characteristics and early outcomes of patients hospitalised for covid-19 in North Zealand, Denmark

AU - Lendorf, Maria Elisabeth

AU - Boisen, Mogens Karsbøl

AU - Kristensen, Peter Lommer

AU - Løkkegaard, Ellen Christine Leth

AU - Krog, Sebastian Moretto

AU - Brandi, Lisbet

AU - Brinth, Louise Schouborg

AU - Nolsöe, Rúna Louise Mortansdóttir

AU - Ryrsø, Camilla

AU - Eiken, Pia

AU - Bestle, Morten Heiberg

AU - Jørgensen, Inger Merete

AU - Pedersen-Bjergaard, Ulrik

AU - Lindegaard, Birgitte

AU - Christensen, Thomas Broe

AU - Fischer, Thea Kølsen

PY - 2020

Y1 - 2020

N2 - INTRODUCTION: Coronavirus disease 2019 (COVID-19) is an ongoing pandemic associated with significant morbidity and mortality worldwide. Limited data are available describing the clinical presentation and outcomes of hospitalised COVID-19 patients in Europe. METHODS:This was a single-centre retrospective chart review of all patients with COVID-19 admitted to the North Zealand Hospital in Denmark between 1 March and 4 May 2020. Main outcomes include major therapeutic interventions during hospitalisation, such as invasive mechanical ventilation, as well as death. RESULTS: A total of 115 patients were included, including four infants. The median age of adults was 68 years and 40% were female. At admission, 55 (50%) patients had a fever, 29 (26%) had a respiratory rate exceeding 24 breaths/minute, and 78 (70%) received supplemental oxygen. The prevalence of co-infection was 13%. Twenty patients (18%) (median age: 64 years; 15% female) were treated in the intensive care unit. Twelve (10.4%) received invasive mechanical ventilation and three (2.6%) renal replacement therapy. Nine patients (8%) developed pulmonary embolism. Sixteen patients (14%) died. Among patients requiring mechanical ventilation (n = 12), seven (6.1%) were discharged alive, four (3.4%) died and one (0.9%) was still hospitalised. CONCLUSION: In this cohort of hospitalised COVID-19 patients, mortality was lower than in other Danish and European case series.

AB - INTRODUCTION: Coronavirus disease 2019 (COVID-19) is an ongoing pandemic associated with significant morbidity and mortality worldwide. Limited data are available describing the clinical presentation and outcomes of hospitalised COVID-19 patients in Europe. METHODS:This was a single-centre retrospective chart review of all patients with COVID-19 admitted to the North Zealand Hospital in Denmark between 1 March and 4 May 2020. Main outcomes include major therapeutic interventions during hospitalisation, such as invasive mechanical ventilation, as well as death. RESULTS: A total of 115 patients were included, including four infants. The median age of adults was 68 years and 40% were female. At admission, 55 (50%) patients had a fever, 29 (26%) had a respiratory rate exceeding 24 breaths/minute, and 78 (70%) received supplemental oxygen. The prevalence of co-infection was 13%. Twenty patients (18%) (median age: 64 years; 15% female) were treated in the intensive care unit. Twelve (10.4%) received invasive mechanical ventilation and three (2.6%) renal replacement therapy. Nine patients (8%) developed pulmonary embolism. Sixteen patients (14%) died. Among patients requiring mechanical ventilation (n = 12), seven (6.1%) were discharged alive, four (3.4%) died and one (0.9%) was still hospitalised. CONCLUSION: In this cohort of hospitalised COVID-19 patients, mortality was lower than in other Danish and European case series.

M3 - Journal article

C2 - 32800073

AN - SCOPUS:85089665212

VL - 67

SP - 1

EP - 11

JO - Danish Medical Journal

JF - Danish Medical Journal

SN - 2245-1919

IS - 9

M1 - A06200428

ER -